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PAEDIATRIC UROLOGY

6.3.5 Antibiotic prophylaxis

Nitrofurantoin and trimethoprim are currently considered as first-line treatment; alternatives are amoxycillin or cephalosporins. Long-term antibiotic prophylaxis is required particularly in children with VRR. Other indications for antibiotic prophylaxis are recurrent cystitis with or without voiding disturbances, medullary sponge kidneys, kidney duplication with reflux to the lower pole, ectopic ureters, dilatation of the upper urinary tract, ureterocele and neurogenic bladder dysfunction (e.g. MMC or tethered chord syndrome).